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149231-66-3

149231-66-3 structure
149231-66-3 structure
  • Name: Ac-YVAD-pNA
  • Chemical Name: (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-(4-nitroanilino)-4-oxobutanoic acid
  • CAS Number: 149231-66-3
  • Molecular Formula: C29H36N6O10
  • Molecular Weight: 628.63
  • Create Date: 2018-12-29 10:02:29
  • Modify Date: 2024-01-08 20:14:40
  • Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes[1][2].

Name (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-(4-nitroanilino)-4-oxobutanoic acid
Synonyms Ac-Tyr-Val-Ala-Asp-PNA
IL-1beta Converting Enzyme (ICE) Colorimetric Substrate
Ac-Tyr-Val-Ala-Asp-paranitroanilide
L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-
N-Acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine
Caspase-1 Substrate IV,Colorimetric
Ac-YVAD-pNA
Density 1.4±0.1 g/cm3
Boiling Point 1108.9±65.0 °C at 760 mmHg
Molecular Formula C29H36N6O10
Molecular Weight 628.63
Flash Point 624.5±34.3 °C
Exact Mass 628.249268
PSA 248.85000
LogP 2.61
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.605
RIDADR NONH for all modes of transport