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  • DC Chemicals Limited
  • China
  • Product Name: Lofexidine
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

31036-80-3

31036-80-3 structure
31036-80-3 structure
  • Name: Lofexidine
  • Chemical Name: lofexidine
  • CAS Number: 31036-80-3
  • Molecular Formula: C11H12Cl2N2O
  • Molecular Weight: 259.132
  • Catalog: API Circulatory system medication Antihypertensive drug
  • Create Date: 2018-09-03 01:15:31
  • Modify Date: 2024-01-04 23:08:25
  • Lofexidine is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal[1][2].

Name lofexidine
Synonyms MFCD00865915
2-{1-[(2,6-dichlorophenyl)oxy]ethyl}-4,5-dihydro-1H-imidazole
2-(a-(2,6-dichlorophenoxy)ethyl)2-imidazoline
Lofexidinum [INN-Latin]
Lofexidina
1H-Imidazole, 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-
Britlofex
Lofexidine
(±)-2-[1-(2,6-Dichlorophenoxy)ethyl]-2-imidazoline
Lofexidinum
Lofexidine [INN:BAN]
Lofexidina [INN-Spanish]
2-[1-(2,6-dichlorophenoxy)ethyl]-2-imidazoline
UNII:UI82K0T627
(-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene
2-[1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole
rac-2-[1-(2,6-dichlorophenoxy)ethyl]-1,3-diazacyclopent-2-ene
Density 1.4±0.1 g/cm3
Boiling Point 421.5±35.0 °C at 760 mmHg
Melting Point 215-225 °C
Molecular Formula C11H12Cl2N2O
Molecular Weight 259.132
Flash Point 208.7±25.9 °C
Exact Mass 258.032654
PSA 33.62000
LogP 3.59
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.611
Storage condition -20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ2568000
CHEMICAL NAME :
2-Imidazoline 2-(1-(2,6-dichlorophenoxy)ethyl)-
CAS REGISTRY NUMBER :
31036-80-3
LAST UPDATED :
198912
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C11-H12-Cl2-N2-O
MOLECULAR WEIGHT :
259.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
8320 ug/kg
SEX/DURATION :
female 8-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
NRTXDN Neurotoxicology. (Intox Press, Inc., POB 34075, Little Rock, AR 72203) V.1- 1979- Volume(issue)/page/year: 9,559,1988
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
8320 ug/kg
SEX/DURATION :
female 8-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
NRTXDN Neurotoxicology. (Intox Press, Inc., POB 34075, Little Rock, AR 72203) V.1- 1979- Volume(issue)/page/year: 9,551,1988
Safety Phrases S24/25
WGK Germany 3