362-29-8
362-29-8 structure
- Name: propiomazine
- Chemical Name: propiomazine
- CAS Number: 362-29-8
- Molecular Formula: C20H24N2OS
- Molecular Weight: 340.48200
- Catalog: API Antiallergic Antihistamine
- Create Date: 2018-02-11 08:00:00
- Modify Date: 2024-01-08 18:50:27
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Propiomazine is an orally active antihistamine agent with sedative effects. Propiomazine can be used in the research of insomnia[1][2].
| Name | propiomazine |
|---|---|
| Synonyms |
Propiomazinum
1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one Propiomazinum [INN-Latin] Propiomazina [INN-Spanish] Wy-1359 Largon Dorevan Phenoctyl 1-[10-(2-dimethylamino-propyl)-10H-phenothiazin-2-yl]-propan-1-one Propionylpromethazine Propiomazina 1-[10-(2-dimethylamino-propyl)-phenothiazin-2-yl]-propan-1-one 10-<2-Dimethylamino-propyl>-3-propionyl-phenothiazin 3-Propionyl-10-<2-dimethylamino-propyl>-phenothiazin 1-[10-(2-Dimethylamino-propyl)-phenothiazin-2-yl]-propan-1-on |
| Description | Propiomazine is an orally active antihistamine agent with sedative effects. Propiomazine can be used in the research of insomnia[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | Propiomazine (0.2 mg/kg, nasal administration, rats) is quickly absorbed, followed by rapid reduction of the plasma concentrations[3]. Propiomazine (25 mg/kg, i.p., at 0 and 3 h after challenge) protects rats against CCl4-induced hepatic injury[4]. Propiomazine (0.31-20 mg/kg, i.v.) increases plasma prolactin concentrations in rats[5]. |
| Density | 1.137g/cm3 |
|---|---|
| Boiling Point | 500.8ºC at 760mmHg |
| Molecular Formula | C20H24N2OS |
| Molecular Weight | 340.48200 |
| Flash Point | 256.7ºC |
| Exact Mass | 340.16100 |
| PSA | 48.85000 |
| LogP | 4.89710 |
|
~%
362-29-8 |
| Literature: Bulletin de la Societe Chimique de France, , p. 1474,1480 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |