Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Peramivir Trihydrate
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Peramivir Trihydrate
Price: ￥428.0/100mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Peramivir Trihydrate
Price: $400.0/100mg $800.0/250mg $1500.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Peramivir Trihydrate
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Peramivir
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

1041434-82-5

1041434-82-5 structure

Name: Peramivir Trihydrate
Chemical Name: peramivir
CAS Number: 1041434-82-5
Molecular Formula: C₁₅H₃₄N₄O₇
Molecular Weight: 382.453
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2018-04-17 08:00:00
Modify Date: 2024-01-01 23:33:39
Peramivir (RWJ 270201; Rapiacta; BCX 1812) is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.IC50 Value: 0.09 nMTarget: NeuraminidasePeramivir is an experimental antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza. It has been authorized for the emergency use of treatment of certain hospitalized patients with known or suspected 2009 H1N1 influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. From Wikipedia

Name	peramivir
Synonyms	Rapiacta trihydrate Peramivir Trihydrate QW7Y7ZR15U peramivir hydrate BCX 1812 trihydrate CS-0732 UNII-QW7Y7ZR15U (1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid,trihydrate (1S,2S,3S,4R)-3-[(1S)-1-Acetamido-2-ethylbutyl]-4-[(diaminomethylene)amino]-2-hydroxycyclopentanecarboxylic acid trihydrate Cyclopentanecarboxylic acid, 3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(diaminomethylene)amino]-2-hydroxy-, (1S,2S,3S,4R)-, hydrate (1:3)

Description	Peramivir (RWJ 270201; Rapiacta; BCX 1812) is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.IC50 Value: 0.09 nMTarget: NeuraminidasePeramivir is an experimental antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza. It has been authorized for the emergency use of treatment of certain hospitalized patients with known or suspected 2009 H1N1 influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. From Wikipedia
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
References	[1]. Louie JK, Yang S, Yen C, Acosta M, Schechter R, Uyeki TM.Use of Intravenous Peramivir for Treatment of Severe Influenza A(H1N1)pdm09.PLoS One. 2012;7(6):e40261. [2]. Sakata H.Clinical efficiency in children treated with intravenous drip infusion of peramivirJpn J Antibiot. 2011 Dec;64(6):383-7. [3]. Abed Y, Pizzorno A, Boivin G.Therapeutic Activity of Intramuscular Peramivir in Mice Infected with a Recombinant Influenza A/WSN/33 (H1N1) Virus Containing the H275Y Neuraminidase Mutation.Antimicrob Agents Chemother. 2012 Aug;56(8):4375-80. [4]. Shobugawa Y, Saito R, Sato I, Kawashima T, Dapat C, Dapat IC, Kondo H, Suzuki Y, Saito K, Suzuki H.Clinical effectiveness of neuraminidase inhibitors-oseltamivir, zanamivir, laninamivir, and peramivir-for treatment of influenza A(H3N2) and A(H1N1)pdm09 infection: an observational study in the 2010-2011 influenza season in Japan.J Infect Chemother. 2012 May 29. [5]. Yu Y, Garg S, Yu PA, Kim HJ, Patel A, Merlin T, Redd S, Uyeki TM.Peramivir use for treatment of hospitalized patients with influenza A(H1N1)pdm09 under emergency use authorization, October 2009-June 2010.Clin Infect Dis. 2012 Jul;55(1):8-15.

Molecular Formula	C₁₅H₃₄N₄O₇
Molecular Weight	382.453
Exact Mass	382.242737
PSA	179.71000
LogP	1.69890

Hazard Codes	Xi

1041434-82-5	612-90-8
330600-85-6	2124296-37-1
229614-55-5	5187-94-0
140846-72-6	773092-05-0
13450-94-7	35387-50-9
1158522-08-7	940364-43-2
1785380-61-1	1803560-73-7
134104-43-1	131615-57-1
6906-52-1	930439-75-1
1018584-77-4	1375289-11-4