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367518-31-8

367518-31-8 structure
367518-31-8 structure
  • Name: Galanin (2-11) amide trifluoroacetate salt
  • Chemical Name: trp-thr-leu-asn-ser-ala-gly-tyr-leu-leu-nh2
  • CAS Number: 367518-31-8
  • Molecular Formula: C54H81N13O14
  • Molecular Weight: 1136.30
  • Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
  • Create Date: 2016-02-15 17:31:47
  • Modify Date: 2024-01-09 11:54:58
  • AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain[1][2].

Name trp-thr-leu-asn-ser-ala-gly-tyr-leu-leu-nh2
Synonyms Dynole 34-2
Galanin (2-11)
Description AR-M1896 is a GalR2 selective agonist with a binding IC50 of 1.76 nM for rat GalR2. AR-M1896 can be used for the research of acute myocardial infarction and neuropathic pain[1][2].
Related Catalog
Target

IC50: 1.76 nM (rat GalR2), 879 nM (hGalR1)[1]

References

[1]. Liu HX, et al. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9960-4.  

[2]. Serebryakova L, et al. Galanin and its N-terminal fragments reduce acute myocardial infarction in rats. Peptides. 2019 Jan;111:127-131.  

Molecular Formula C54H81N13O14
Molecular Weight 1136.30
Exact Mass 1135.60000
PSA 450.58000
LogP 2.49160