- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Racecadotril
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Racecadotril
- Price: ￥248.0/1g ￥538.0/5g
- Purity: 99.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Racecadotril
- Price: $300.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Racecadotril
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Racecadotril
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
81110-73-8
81110-73-8 structure
- Name: Racecadotril
- Chemical Name: Racecadotril
- CAS Number: 81110-73-8
- Molecular Formula: C21H23NO4S
- Molecular Weight: 385.477
- Catalog: API Digestive system medication Laxative antidiarrheal
- Create Date: 2018-08-24 18:08:44
- Modify Date: 2024-01-02 11:59:08
-
Racecadotril (acetorphan), a potent enkephalinase inhibitor (IC50= 4.5 uM), protects endogenous enkephalins from degradation. IC50 value: 4.5 uMTarget: EnkephalinaseRacecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 uM. Unlike other medications used to treat diarrhea, which reduce intestinal motility, Racecadotril has an antisecretory effect-it reduces the secretion of water and electrolytes into the intestine. A small randomized controlled trial found Racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy.
| Name | Racecadotril |
|---|---|
| Synonyms |
Acetorphan
Tiorfan Hidrasec Tiorfix Redotil MFCD00865520 Benzyl N-[3-(acetylsulfanyl)-2-benzylpropanoyl]glycinate Racecadotril RACECADOTRIL: ACETORPHAN RACECADORTRIL Glycine, N-[3-(acetylthio)-1-oxo-2-(phenylmethyl)propyl]-, phenylmethyl ester |
| Description | Racecadotril (acetorphan), a potent enkephalinase inhibitor (IC50= 4.5 uM), protects endogenous enkephalins from degradation. IC50 value: 4.5 uMTarget: EnkephalinaseRacecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 uM. Unlike other medications used to treat diarrhea, which reduce intestinal motility, Racecadotril has an antisecretory effect-it reduces the secretion of water and electrolytes into the intestine. A small randomized controlled trial found Racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy. |
|---|---|
| Related Catalog | |
| References |
[5]. Racecadotril |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 574.5±50.0 °C at 760 mmHg |
| Melting Point | 89ºC |
| Molecular Formula | C21H23NO4S |
| Molecular Weight | 385.477 |
| Flash Point | 301.2±30.1 °C |
| Exact Mass | 385.134766 |
| PSA | 97.77000 |
| LogP | 3.44 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.579 |
| Storage condition | Refrigerator |
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H400 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Codes | Xn,N |
| Risk Phrases | 22-50/53 |
| Safety Phrases | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
| RTECS | MB7606872 |
| HS Code | 2930909090 |
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |