Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 3,4'-Dihydroxyflavone
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

BioBioPha
China
Product Name: 3,4'-Dihydroxyflavone
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng

14919-49-4

14919-49-4 structure

14919-49-4 structure

Name: 3,4'-Dihydroxyflavone
Chemical Name: 3-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
CAS Number: 14919-49-4
Molecular Formula: C₁₅H₁₀O₄
Molecular Weight: 254.24
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2018-04-11 08:00:00
Modify Date: 2024-01-03 18:03:49
3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1].

Name	3-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
Synonyms	3-Hydroxy-2-(4-hydroxyphenyl)chromone 4'-Hydroxyflavonol 3-hydroxy-2-(4-hydroxy-phenyl)-chromen-4-one 3,4'-dihydroxyfavone 3-Hydroxy-2-(4-hydroxy-phenyl)-chromen-4-on 3,4'-dihydroxyfalvone 3,4'-Dihydroxyflavone

Description	3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid with antiviral activity against Influenza A virus[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
In Vivo	3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1]. Animal Model: 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1]. Dosage: 1 mg/kg per 30 μL. Administration: Oral administration daily for 5 days. Result: Significantly decreased virus titers and pathological changes in the lung and reduced body weight loss and death.
References	[1]. Hossain MK, et al. Antiviral activity of 3,4'-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6.

Density	1.472g/cm3
Boiling Point	452.5ºC at 760mmHg
Melting Point	275-276ºC
Molecular Formula	C₁₅H₁₀O₄
Molecular Weight	254.24
Flash Point	175.7ºC
Exact Mass	254.05800
PSA	70.67000
LogP	2.87120
Vapour Pressure	5.61E-09mmHg at 25°C
Index of Refraction	1.712

HS Code	2914501900

HS Code	2914501900
Summary	2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%