22242-89-3

22242-89-3 structure

Name: NSC 107512
Chemical Name: 7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 4-amino-N-hydroxy-7-.β.-D-ribofuranosyl
CAS Number: 22242-89-3
Molecular Formula: C₁₂H₁₆N₆O₅
Molecular Weight: 324.29300
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2017-06-28 07:10:45
Modify Date: 2024-01-07 20:55:11
NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors[1].

Name	7H-Pyrrolo[2,3-d]pyrimidine-5-carboximidamide, 4-amino-N-hydroxy-7-.β.-D-ribofuranosyl

Description	NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK9[1]
References	[1]. Dolloff NG, et al. Sangivamycin-like molecule 6 exhibits potent anti-multiple myeloma activity through inhibition of cyclin-dependent kinase-9. Mol Cancer Ther. 2012;11(11):2321-2330.