15049-50-0

15049-50-0 structure

Name: Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI)
Chemical Name: [3,4-dibenzoyloxy-5-(2-oxo-4-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methyl benzoate
CAS Number: 15049-50-0
Molecular Formula: C₃₀H₂₄N₂O₈S
Molecular Weight: 572.59
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-12-29 10:11:10
Modify Date: 2024-01-10 18:58:31
2’,3’,5’-Tri-O-benzoyl-4-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	[3,4-dibenzoyloxy-5-(2-oxo-4-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methyl benzoate
Synonyms	O2',O3',O5'-Tribenzoyl-4-thio-uridin 2',3',5'-tribenzoyl 4-thiouridine 2',3',5'-Tri-O-benzoyl-4-thio-uridin O2',O3',O5'-tribenzoyl-4-thio-uridine 2',3',5'-tri-O-benzoyl-4-thiouridine

Description	2’,3’,5’-Tri-O-benzoyl-4-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

1748-04-5

15049-50-0

Literature: Xu, Yao-Zhong; Zheng, Qinguo; Swann, Peter F. Tetrahedron Letters, 1991 , vol. 32, # 24 p. 2817 - 2820

98-88-4

15049-50-0

Literature: Fox et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 178,187

58-96-8

15049-50-0

Literature: Fox et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 178,187