23246-96-0

23246-96-0 structure

Name: Riddelline
Chemical Name: riddelliine
CAS Number: 23246-96-0
Molecular Formula: C₁₈H₂₃NO₆
Molecular Weight: 349.37800
Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
Create Date: 2016-01-27 22:15:27
Modify Date: 2024-01-19 17:26:44
Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver[1].

Name	riddelliine
Synonyms	13,19-Didehydro-12,18-dihydroxysenecionan-11,16-dione Riddeline Riddelliine Riddeliine 12,18-dihydroxy-senecion-13(19)-ene-11,16-dione Riddeliin (15Z)-12,18-dihydroxy-13,19-didehydrosenecionan-11,16-dione Riddelline

Description	Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Others
References	[1]. J C Mirsalis, et al. In Vivo Measurement of Unscheduled DNA Synthesis and S-phase Synthesis as an Indicator of Hepatocarcinogenesis in Rodents. 5.097Q1 Cell Biol Toxicol. 1987 Jun;3(2):165-73.