34627-62-8

34627-62-8 structure

Name: 3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE
Chemical Name: 1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
CAS Number: 34627-62-8
Molecular Formula: C₂₉H₂₇ClN₂O₄
Molecular Weight: 502.99
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-10-05 19:58:59
Modify Date: 2024-01-10 17:57:57
3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-[(2R,4S,5R)-4-chloro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Synonyms	3'-Chloro-3'-deoxy-5'-O-(triphenylmethyl)thymidine 3'-Chloro-3'-deoxy-5'-O-tritylthymidine 3'-chloro-O5'-trityl-3'-deoxy-thymidine 3'-Chlor-3'-desoxy-5'-O-tritylthymidin 5'-O-trityl-3'-chlorothymidine

Description	3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Precursor 1
42214-24-4
DownStream 0