60658-40-4

60658-40-4 structure

Name: Undecanoic acid-d21
Chemical Name: dodecanoic-d23 acid
CAS Number: 60658-40-4
Molecular Formula: C₁₁HD₂₁O₂
Molecular Weight: 207.42
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2018-03-10 08:00:00
Modify Date: 2024-01-08 22:08:03
Undecanoic acid-d21 is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

Name	dodecanoic-d23 acid
Synonyms	perdeuterated formic acid Perdeuterated undecanoic acid Formic acid-d2 deuterated formic acid

Description	Undecanoic acid-d21 is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Anti-infection >> Fungal
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Hornung B, et al. Medium chain length fatty acids stimulate triacylglycerol synthesis in tissue culture cells. Biochem Pharmacol. 1992 Jan 22;43(2):175-81. [3]. Das SK, et al. Effect of undecanoic acid on phospholipid metabolism in Trichophyton rubrum. Sabouraudia. 1982 Dec;20(4):267-72. [4]. Das SK, et al. Effect of undecanoic acid on the production of exocellular lipolytic and keratinolytic enzymes by undecanoic acid-sensitive and -resistant strains of Trichophyton rubrum. Sabouraudia. 1982 Sep;20(3):179-84. [5]. Coppa M, et al. Effect of a hay-based diet or different upland grazing systems on milk volatile compounds. J Agric Food Chem. 2011 May 11;59(9):4947-54.

Boiling Point	225ºC100 mm Hg(lit.)
Melting Point	44-46ºC(lit.)
Molecular Formula	C₁₁HD₂₁O₂
Molecular Weight	207.42
Flash Point	134.1ºC
Exact Mass	207.29400
PSA	37.30000
LogP	3.60180

Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	26-28

112-37-8

60658-40-4

Literature: Poupko, R.; Luz, Z.; Spielberg, N.; Zimmermann, H. Journal of the American Chemical Society, 1989 , vol. 111, # 16 p. 6094 - 6105

Precursor 1
112-37-8
DownStream 0

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