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1672-46-4

1672-46-4 structure
1672-46-4 structure
  • Name: Digoxigenin
  • Chemical Name: digoxigenin
  • CAS Number: 1672-46-4
  • Molecular Formula: C23H34O5
  • Molecular Weight: 390.51300
  • Catalog: analytical chemistry Standard Forensic and veterinary standards
  • Create Date: 2018-02-05 08:00:00
  • Modify Date: 2024-01-02 17:54:11
  • Digoxigenin is a hapten, a small molecule with high antigenicity, that is used in many molecular biology applications, as an alternative probe labeling for in situ hybridization

Name digoxigenin
Synonyms Lanadigenin
digitoxigenin
MFCD00871861
Lanadigigenin
3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3,12,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
Digoxigenine
Digoxigenin
EINECS 216-806-2
Description Digoxigenin is a hapten, a small molecule with high antigenicity, that is used in many molecular biology applications, as an alternative probe labeling for in situ hybridization
Related Catalog
Density 1.297 g/cm3
Boiling Point 589.4ºC at 760 mmHg
Melting Point 222 °C(lit.)
Molecular Formula C23H34O5
Molecular Weight 390.51300
Flash Point 203ºC
Exact Mass 390.24100
PSA 86.99000
LogP 2.57510
Vapour Pressure 2.4E-16mmHg at 25°C
Index of Refraction 1.609
Storage condition 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FH5390000
CHEMICAL NAME :
5-beta-Card-20(22)-enolide, 3-beta,12-beta,14-trihydroxy-
CAS REGISTRY NUMBER :
1672-46-4
BEILSTEIN REFERENCE NO. :
0096479
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C23-H34-O5
MOLECULAR WEIGHT :
390.57
WISWESSER LINE NOTATION :
L E5 B666TJ A1 DQ E1 F- DT5OV CUTJ IQ OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
244 ug/kg
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting
REFERENCE :
JPHAA3 Journal of the American Pharmaceutical Association. (Washington, DC) V.1-28, 1912-39; New series: V.1-17, 1961-77. Volume(issue)/page/year: 27,189,1938
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
285 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,55,1963
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
3545 ug/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Cardiac - other changes
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 153,436,1965
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Bird - pigeon
DOSE/DURATION :
1620 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 8,18,1960 *** REVIEWS *** TOXICOLOGY REVIEW 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,190,1963
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H300-H310-H330
Precautionary Statements P260-P264-P280-P284-P302 + P350-P310
Hazard Codes T+: Very toxic;
Risk Phrases R26/27/28
Safety Phrases S36/37/39-S45
RIDADR UN 2811 6.1/PG 1
WGK Germany 3
RTECS FH5390000
Packaging Group II
Hazard Class 6.1(a)