Name | 1-(1-Methoxy-2-butanyl)-N-(4-methoxy-2-methylphenyl)-6-methyl-1H- [1,2,3]triazolo[4,5-c]pyridin-4-amine |
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Description | SN003 is a reversible antagonist of corticotropin releasing factor receptor 1 (CRFR 1) (IC50 = 241 nM) that displays more than 1000-fold selectivity over CRFR 2. SN003 suppresses CRF-induced ACTH release in vitro. SN003 attenuates depressive-like behavior in rat[1][2][3]. |
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Related Catalog | |
References |
Molecular Formula | C19H25N5O2 |
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Molecular Weight | 355.43400 |
Exact Mass | 355.20100 |
PSA | 74.09000 |
LogP | 3.86580 |