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304008-29-5

304008-29-5 structure
304008-29-5 structure
  • Name: LU AA33810
  • Chemical Name: N-{[trans-4-(4,5-Dihydro[1]benzothiepino[5,4-d][1,3]thiazol-2-yla mino)cyclohexyl]methyl}methanesulfonamide
  • CAS Number: 304008-29-5
  • Molecular Formula: C19H25N3O2S3
  • Molecular Weight: 423.61600
  • Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
  • Create Date: 2017-06-10 05:28:25
  • Modify Date: 2024-01-31 19:24:04
  • Lu AA33810 is a potent and selective antagonist of neuropeptide Y5 receptor with a Ki of 1.5 nM for the human receptor. Lu AA33810 exhibts antianxiolytic-like and antidepressant-like effects[1].

Name N-{[trans-4-(4,5-Dihydro[1]benzothiepino[5,4-d][1,3]thiazol-2-yla mino)cyclohexyl]methyl}methanesulfonamide
Description Lu AA33810 is a potent and selective antagonist of neuropeptide Y5 receptor with a Ki of 1.5 nM for the human receptor. Lu AA33810 exhibts antianxiolytic-like and antidepressant-like effects[1].
Related Catalog
Target

hY5 receptor:1.5 nM (Ki)

References

[1]. Walker MW, et al. The novel neuropeptide Y Y5 receptor antagonist Lu AA33810 [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects in rat models of stress sensitivity. J Pharmacol Exp Ther. 2009 Mar;328(3):900-11.

Molecular Formula C19H25N3O2S3
Molecular Weight 423.61600
Exact Mass 423.11100
PSA 136.24000
LogP 4.87180