Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Fluorescein isothiocyanate
Price: ￥158.0/100mg ￥538.0/500mg
Purity: 90.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: FITC
Price: $200.0/1g $150.0/10ml
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

ShangHai DC Chemicals Co.,Ltd
China
Product Name: FITC
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Fluorescein isothiocyanate isomer I
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

3326-32-7

3326-32-7 structure

Name: Fluorescein isothiocyanate
Chemical Name: fluorescein 5-isothiocyanate
CAS Number: 3326-32-7
Molecular Formula: C₂₁H₁₁NO₅S
Molecular Weight: 389.381
Catalog: Chemical reagent Organic reagent Ester Other ester compounds
Create Date: 2018-07-02 20:13:38
Modify Date: 2024-01-02 06:13:12
FITC is a derivative of fluorescein for the labeling of amines.

Name	fluorescein 5-isothiocyanate
Synonyms	5-FITC Isothiocyanatofluorescein 5-Isothionatofluorescein Benzoic acid, 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-isothiocyanato- FITC Fluorescein 5-isothiocyanate EINECS 248-207-7 Fluorescein Isothiosyanate fluorescein isothiocyanate isomer 1 fluorescein 6-isothiocyanate FITC ISOMER Fluorescein 5-Isothiocyanate (isomer I) 3',6'-Dihydroxy-5-isothiocyanato-3H-spiro[2-benzofurane-1,9'-xanthén]-3-one 5-FITC (isomer I) 5-Isothiocyanatofluorescein (isomer I) FITC 5-Fluorescein Isothiocyanate fluorescein 5-isothiocyanate FITC,Fluorescein 5-isothiocyanate FITC isomer I Fluorescein isothiocyanate,isomer 1 2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-5-isothiocyanatobenzoic acid Fluorescein Isothiocyanate (isomer I) Fluorescein isothiocyanate isomer I Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-5-isothiocyanato- FITC-I Fluorescein 5(6)-isothiocyanate Fluorescein-5-isothiocyanate MFCD00005063 Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-5-isothiocyanato- Fluorescein Isothiocyanate 3',6'-Dihydroxy-5-isothiocyanato-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one

Description	FITC is a derivative of fluorescein for the labeling of amines.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
In Vitro	Annexin V-FITC/PI is employed to detect chondrocyte apoptosis[1]. The PEI-modified CDs are conjugated with fluorescein isothiocyanate (FITC) to fabricate CDs-FITC composites[2].
Cell Assay	The frequency of chondrocyte apoptosis is measured by flow cytometry with Annexin V-fluorescein isothiocyanate (FITC) and propidium iodide. A total of 1×104 treated chondrocytes are collected from each group, washed in cold PBS and incubated with Annexin V-FITC and PI at room temperature for 15 min in the dark on ice. These samples are then analyzed using a fluorescence-activated cell sorter. Cell Quest software is used to analyze the percentage of apoptosis. All tests are repeated in triplicate.
References	[1]. Gao SG, et al. Phosphorylation of osteopontin has proapoptotic and proinflammatory effects on human knee osteoarthritis chondrocytes. Exp Ther Med. 2016 Nov;12(5):3488-3494. Epub 2016 Oct 5. [2]. Zhu X, et al. Ratiometric, visual, dual-signal fluorescent sensing and imaging of pH/copper ions in real samples based on carbon dots-fluorescein isothiocyanate composites. Talanta. 2017 Jan 1;162:65-71

Density	1.5±0.1 g/cm3
Boiling Point	708.6±60.0 °C at 760 mmHg
Melting Point	>360 °C(lit.)
Molecular Formula	C₂₁H₁₁NO₅S
Molecular Weight	389.381
Flash Point	382.4±32.9 °C
Exact Mass	389.035797
PSA	120.44000
LogP	4.00
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.754
Storage condition	2-8°C
Stability	Stability Stable, but moisture-sensitive. Incompatible with strong oxidizing agents, strong bases, amines, acids.
Water Solubility	practically insoluble

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H317-H334
Precautionary Statements	P261-P280-P342 + P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22;R36/37/38;R42/43
Safety Phrases	S22-S45-S36/37/39-S26-S36/37
RIDADR	NONH for all modes of transport
WGK Germany	3

2321-07-5

3326-32-7

Literature: WO2006/84339 A1, ; Page/Page column 30 ;

463-71-8

3326-34-9

3326-32-7

Literature: Tomasch, Miriam; Schwed, J. Stephan; Kuczka, Karina; Meyer Dos Santos, Sascha; Harder, Sebastian; Nuesing, Rolf M.; Paulke, Alexander; Stark, Holger ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 9 p. 774 - 779

610-27-5

3326-32-7

Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779

108-46-3

3326-32-7

Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779

3326-35-0

3326-32-7

Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779

14926-29-5

3326-32-7

Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779

Precursor 7
2321-07-5 463-71-8 3326-34-9 610-27-5
108-46-3 3326-35-0 14926-29-5
DownStream 0

3326-32-7	27072-45-3
3326-31-6	18861-78-4
1173-43-9	76391-89-4
60842-46-8	116843-39-1
63469-13-6	82420-81-3
75593-62-3	1158522-08-7
940364-43-2	134104-43-1
131615-57-1	6906-52-1
1019098-18-0	930439-75-1
882281-68-7	1018584-77-4