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80734-02-7

80734-02-7 structure
80734-02-7 structure
  • Name: Lenampicillin hydrochloride
  • Chemical Name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride
  • CAS Number: 80734-02-7
  • Molecular Formula: C21H24ClN3O7S
  • Molecular Weight: 497.95
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2018-06-05 08:00:00
  • Modify Date: 2024-01-01 20:52:09
  • Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.
Name (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate,hydrochloride
Synonyms lenampicillin hydrochloride
Lenampicillin hydrochloride (JP16)
Valacillin (TN)
Lenampicillin (hydrochloride)
Description Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.
Related Catalog
References

[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93.

[2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.
Boiling Point 717.4ºC at 760 mmHg
Molecular Formula C21H24ClN3O7S
Molecular Weight 497.95
Flash Point 387.7ºC
PSA 170.38000
LogP 1.86060
Storage condition 2-8℃

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title: CAS No. 80734-02-7 | Chemsrc address: https://www.chemsrc.com/en/baike/443591.html

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