Name | Lenampicillin-d5 hydrochloride |
---|
Description | Lenampicillin-d5 (KBT 1585-d5) hydrochloride is the deuterium labeled Lenampicillin hydrochloride. Lenampicillin hydrochloride (KBT 1585 hydrochloride) is an orally active prodrug of Ampicillin and is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins (transpeptidase). Lenampicillin hydrochloride has improved absorption and decreased side effects compares to Ampicillin and is applied in the investigation of the suppurative skin and soft tissue infection[1][2][3]. |
---|---|
Related Catalog | |
In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
References |
[2]. FUMIO OGINO, et al. ACUTE TOXICITY OF LENAMPICILLIN HYDROCHLORIDE (KBT-1585) IN MICE, RATS AND DOGS |
Molecular Formula | C21H19D5ClN3O7S |
---|---|
Molecular Weight | 502.98 |