Top Suppliers:I want be here
Related CAS#:
7336-40-5 477-30-5
1246817-95-7 103394-70-3
58068-80-7 3938-45-2
10162-76-2 21248-24-8
142060-54-6 101622-73-5

7336-40-5

7336-40-5 structure
7336-40-5 structure
  • Name: N-Methylcolchicine
  • Chemical Name: N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
  • CAS Number: 7336-40-5
  • Molecular Formula: C15H16O4
  • Molecular Weight: 260.29
  • Catalog: Research Areas Others
  • Create Date: 2018-06-16 21:37:47
  • Modify Date: 2024-01-10 18:20:38
  • Micromarin F (compound 9) is synthesized from osthole. Micromarin F against Balanus albicostatus and Bugula neritina with EC50 values of 10.93 and 12.38 μM[1].
Name N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Synonyms N-Methylcolchicine
COLCHICINE,N-METHYL
Desacetylamino-N-methylcolchiceinamid
N-Acetyldemecolcine
N-methyl-N-((S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide
N-acetyldemecoline
N-Methyl-N-((S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamid
N-Methyl-colchicin
N-Acetylcolchamine
Acetamide,N-methyl-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)
N-Acetylcolcemid
Description Micromarin F (compound 9) is synthesized from osthole. Micromarin F against Balanus albicostatus and Bugula neritina with EC50 values of 10.93 and 12.38 μM[1].
Related Catalog
References

[1]. Zhan-Chang Wang, et al. Coumarins from the Herb Cnidium monnieri and Chemically Modified Derivatives as Antifoulants against Balanus albicostatus and Bugula neritina Larvae. Int. J. Mol. Sci. 2013, 14.

Density 1.24g/cm3
Boiling Point 683.2ºC at 760 mmHg
Molecular Formula C15H16O4
Molecular Weight 260.29
Flash Point 367ºC
Exact Mass 413.18400
PSA 74.30000
LogP 3.21380
Index of Refraction 1.583

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GH0890000
CHEMICAL NAME :
Colchicine, N-methyl-
CAS REGISTRY NUMBER :
7336-40-5
BEILSTEIN REFERENCE NO. :
2825013
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C23-H27-N-O6
MOLECULAR WEIGHT :
413.51
WISWESSER LINE NOTATION :
L B677 MV&T&J CO1 DO1 EO1 JN1&V1 NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3400 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,284,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2900 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea
REFERENCE :
PHTXA6 Pharmacology and Toxicology. English translation of FATOAO. (New York, NY) V.20-22, 1957-59. Discontinued. Volume(issue)/page/year: 20,284,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1445 ug/kg
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,257,1981
Hazard Codes Xi
477-30-5 structure

477-30-5
108-24-7 structure

108-24-7

~95%

7336-40-5 structure

7336-40-5
Literature: Hufford; Capraro; Brossi Helvetica Chimica Acta, 1980 , vol. 63, # 1 p. 50 - 56
7359-91-3 structure

7359-91-3

~%

7336-40-5 structure

7336-40-5
Literature: Santavy Collection of Czechoslovak Chemical Communications, 1959 , vol. 24, p. 2237,2242
186581-53-3 structure

186581-53-3

~%

7336-40-5 structure

7336-40-5
Literature: Uffer et al. Helvetica Chimica Acta, 1954 , vol. 37, p. 18,29
186581-53-3 structure

186581-53-3

~%

7404-91-3 structure

7404-91-3
7336-40-5 structure

7336-40-5
Literature: Uffer et al. Helvetica Chimica Acta, 1954 , vol. 37, p. 18,29
67-56-1 structure

67-56-1
477-27-0 structure

477-27-0
124-41-4 structure

124-41-4
74-88-4 structure

74-88-4

~%

Detail
Literature: Uffer et al. Helvetica Chimica Acta, 1954 , vol. 37, p. 18,29

Chemsrc provides CAS#:7336-40-5 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 7336-40-5 | Chemsrc address: https://www.chemsrc.com/en/baike/446917.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved