902523-58-4

902523-58-4 structure

Name: ML-261
Chemical Name: 2-Chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methyl-4H-thieno[3,2-b ]pyrrole-5-carboxamide
CAS Number: 902523-58-4
Molecular Formula: C₂₀H₂₃ClN₂O₃S
Molecular Weight: 406.926
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-12-01 14:56:45
Modify Date: 2024-02-23 12:20:53
ML261 is a hepatic lipid droplets formation inhibitor with an IC50 value of 69.7 nM. ML261 can be used for the research of non-alcoholic fatty liver disease (NAFLD) and inflammation[1].

Name	2-Chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methyl-4H-thieno[3,2-b ]pyrrole-5-carboxamide
Synonyms	2-Chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methyl-4H-thieno[3,2-b]pyrrole-5-carboxamide 4H-Thieno[3,2-b]pyrrole-5-carboxamide, 2-chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methyl-

Description	ML261 is a hepatic lipid droplets formation inhibitor with an IC50 value of 69.7 nM. ML261 can be used for the research of non-alcoholic fatty liver disease (NAFLD) and inflammation[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: 69.7 nM (hepatic lipid droplets formation)[1]
In Vitro	ML261 (1 nM-10 μM; 24 h) affects hepatic lipid droplets formation in murine AML-12 cells[1]. Cell Viability Assay[1] Cell Line: AML-12 cells Concentration: 1 nM-10 μM Incubation Time: 24 hours Result: Inhibited hepatic lipid droplets formation with an IC50 value of 69.7 nM.
References	[1]. Zou J, et al. Potent inhibitors of lipid droplet formation. 2014.