Name | (r)-dpn |
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Synonyms |
(2R)-2,3-Bis(4-hydroxyphenyl)propanenitrile
DMAB-anabaseine dihydrochloride Benzenepropanenitrile, 4-hydroxy-α-(4-hydroxyphenyl)-, (αR)- |
Description | R)-DPN (compound 3) is a selective ERβ ligand with EC50s of 2.9, 0.8 nM for ERα and ERβ, respectively. (R)-DPN shows a very high affinity and potency preference for ERβ over ERα. (R)-DPN shows cytoxicity for HEC-1 and U2OS cells with EC50s of 286, 205 nM, respectively[1]. |
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Related Catalog | |
Target |
ERα:2.9 nM (EC50) ERβ:0.8 nM (EC50) |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 449.4±35.0 °C at 760 mmHg |
Molecular Formula | C15H13NO2 |
Molecular Weight | 239.269 |
Flash Point | 225.6±25.9 °C |
Exact Mass | 239.094635 |
PSA | 64.25000 |
LogP | 2.06 |
Vapour Pressure | 0.0±1.1 mmHg at 25°C |
Index of Refraction | 1.640 |