98320-39-9
98320-39-9 structure
- Name: IX 207-887
- Chemical Name: Acetic acid, 2-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)
- CAS Number: 98320-39-9
- Molecular Formula: C16H12O3S
- Molecular Weight: 284.33000
- Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
- Create Date: 2017-07-25 08:14:46
- Modify Date: 2024-01-02 18:35:32
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IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).
| Name | Acetic acid, 2-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene) |
|---|---|
| Synonyms |
IX 207887
4H-Benzo[4,5]cyclohepta[1,2-b]thiophene, acetic acid deriv. (Z)-10-METHOXY-4H-BENZO[4,5]CYCLOHEPTA[1,2-B]THIOPHENE-4-YLIDENE ACETIC ACID Acetic acid, (10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)- IX 207-887 |
| Description | IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1). |
|---|---|
| Related Catalog | |
| Target |
Interleukin-1[1] |
| In Vitro | IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed[1]. |
| References |
| Molecular Formula | C16H12O3S |
|---|---|
| Molecular Weight | 284.33000 |
| Exact Mass | 284.05100 |
| PSA | 74.77000 |
| LogP | 3.72230 |
| HS Code | 2934999090 |
|---|
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |