- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Falcarinol
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- BioBioPha
- China
- Product Name: Falcarinol
- Price: ￥2250.0/5mg
- Purity: 93.0%
- Stocking Period: 10 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Falcarinol
- Price: ￥4418.0/5mg ￥3728.0/20mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Falcarinol
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: falcarinol
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
21852-80-2
21852-80-2 structure
- Name: Falcarinol
- Chemical Name: 1,9-Heptadecadiene-4,6-diyn-3-ol
- CAS Number: 21852-80-2
- Molecular Formula: C17H24O
- Molecular Weight: 244.372
- Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
- Create Date: 2018-07-01 07:29:09
- Modify Date: 2024-01-02 23:18:20
-
Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1].
| Name | 1,9-Heptadecadiene-4,6-diyn-3-ol |
|---|---|
| Synonyms |
Carotatoxin
(-)-Falcarinol (-)-Carotatoxin 1,9-Heptadecadiene-4,6-diyn-3-ol, (3R,9Z)- (-)-Panaxynol (−)-(3R)-falcarinol (3R,9Z)-1,9-Heptadecadiene-4,6-diyn-3-ol Falcarinol Panaxynol (3R,9Z)-Heptadeca-1,9-diene-4,6-diyn-3-ol Falcarinol |
| Description | Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Panaxynol inhibits the sphere-forming ability of NSCLC CSCs by inducing apoptosis. Panaxynol suppresses the viability of NSCLC cells with no effects on normal cells[1]. |
| References |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 370.6±42.0 °C at 760 mmHg |
| Molecular Formula | C17H24O |
| Molecular Weight | 244.372 |
| Flash Point | 163.4±20.9 °C |
| Exact Mass | 244.182709 |
| PSA | 20.23000 |
| LogP | 6.96 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.507 |
| HS Code | 2905290000 |
|---|
|
~69%
21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~40%
21852-80-2 |
| Literature: McLaughlin, Noel P.; Butler, Eibhlin; Evans, Paul; Brunton, Nigel P.; Koidis, Anastasios; Rai, Dilip K. Tetrahedron, 2010 , vol. 66, # 51 p. 9681 - 9687 |
|
~%
21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~%
21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~%
21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~%
21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~%
21852-80-2 |
| Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121 |
|
~%
21852-80-2 |
| Literature: Zheng, Guangrong; Lu, Wei; Aisa, Haji A.; Cai, Junchao Tetrahedron Letters, 1999 , vol. 40, # 11 p. 2181 - 2182 |
| Precursor 5 | |
|---|---|
| DownStream 0 | |
| HS Code | 2905290000 |
|---|---|
| Summary | 2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |