Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Mal-C6-amine TFA
Price: ￥508.0/25mg ￥1218.0/100mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Mal-C6-amine TFA
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-(6-AMINOHEXYL)-1H-PYRROLE-2,5-DIONE 2,2,2-TRIFLUOROACETATE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

731862-92-3

731862-92-3 structure

731862-92-3 structure

Name: Mal-C6-amine TFA
Chemical Name: 1-(6-Aminohexyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate
CAS Number: 731862-92-3
Molecular Formula: C₁₂H₁₇F₃N₂O₄
Molecular Weight: 310.270
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-24 10:20:05
Modify Date: 2024-01-11 17:52:26
Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1-(6-Aminohexyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate
Synonyms	1-(6-aminohexyl)pyrrole-2,5-dione,2,2,2-trifluoroacetic acid 1-(6-Aminohexyl)-1H-pyrrole-2,5-dione trifluoroacetate (1:1) Acetic acid, 2,2,2-trifluoro-, compd. with 1-(6-aminohexyl)-1H-pyrrole-2,5-dione (1:1)

Description	Mal-C6-amine (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₂H₁₇F₃N₂O₄
Molecular Weight	310.270
Exact Mass	310.114044
PSA	100.70000
LogP	1.70200

Hazard Codes	Xi
HS Code	2925190090

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%