358730-99-1

358730-99-1 structure

Name: (12-2H1)Hexadecanoic acid
Chemical Name: hexadecanoic-12-d1 acid
CAS Number: 358730-99-1
Molecular Formula: C₁₆H₃₁DO₂
Molecular Weight: 257.43
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2018-02-21 08:00:00
Modify Date: 2024-01-14 07:09:56
Palmitic acid-d1 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

Name	hexadecanoic-12-d1 acid
Synonyms	(12-H)Hexadecanoic acid Hexadecanoic-12-d acid

Description	Palmitic acid-d1 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Harada H, et al. Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga. Anticancer Res. 2002 Sep-Oct;22(5):2587-90.