178928-68-2

178928-68-2 structure

Name: NGD 94-1
Chemical Name: 2-{4-[(2-Phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl}pyrimidine
CAS Number: 178928-68-2
Molecular Formula: C₁₈H₂₀N₆
Molecular Weight: 320.39
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2016-07-05 23:14:17
Modify Date: 2025-09-27 15:52:17
NGD94-1 is a specific dopamine D4 receptor antagonist. NGD94-1 can effectively reverse Phencyclidine-induced cognitive impairment in marmosets. NGD94-1 can be used in the study of psychiatric diseases[1].

Name	2-{4-[(2-Phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl}pyrimidine

Description	NGD94-1 is a specific dopamine D4 receptor antagonist. NGD94-1 can effectively reverse Phencyclidine-induced cognitive impairment in marmosets. NGD94-1 can be used in the study of psychiatric diseases[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
References	[1]. Jentsch JD, et al. Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys. Psychopharmacology (Berl). 1999 Feb;142(1):78-84.