14317-68-1

14317-68-1 structure

Name: [Asu1,6]-Oxytocin
Chemical Name: deamino-dicarba-oxytocin
CAS Number: 14317-68-1
Molecular Formula: C₄₅H₆₉N₁₁O₁₂
Molecular Weight: 956.09600
Catalog: Research Areas Metabolic Disease
Create Date: 2018-12-31 17:21:11
Modify Date: 2024-01-13 20:57:28
[Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes[1].

Name	deamino-dicarba-oxytocin
Synonyms	tyr-ile-gln-asn-asu-pro-leu-gly-nh2

Description	[Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	[Asu1,6]-Oxytocin (4 μg per injection; third-ventricle injection, twice injected for 7 days) 改善小鼠的葡萄糖耐受不良并降低空腹血胰岛素水平[1]。 Animal Model: C57BL/6 mice[1] Dosage: 4 μg per injection Administration: Third-ventricle injection, twice injected for 7 days Result: Improved glucose intolerance and lowered fasting blood insulin levels, and both effects were independent of body weight.
References	[1]. Zhang H, et al. Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models. PLoS One. 2013 May 20;8(5):e61477.