[Asu1,6]-Oxytocin

Modify Date: 2024-01-13 20:57:28

[Asu1,6]-Oxytocin Structure
[Asu1,6]-Oxytocin structure
Common Name [Asu1,6]-Oxytocin
CAS Number 14317-68-1 Molecular Weight 956.09600
Density 1.216g/cm3 Boiling Point 1475.3ºC at 760 mmHg
Molecular Formula C45H69N11O12 Melting Point N/A
MSDS N/A Flash Point 846ºC

 Use of [Asu1,6]-Oxytocin


[Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes[1].

 Names

Name deamino-dicarba-oxytocin
Synonym More Synonyms

 [Asu1,6]-Oxytocin Biological Activity

Description [Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes[1].
Related Catalog
In Vivo [Asu1,6]-Oxytocin (4 μg per injection; third-ventricle injection, twice injected for 7 days) 改善小鼠的葡萄糖耐受不良并降低空腹血胰岛素水平[1]。 Animal Model: C57BL/6 mice[1] Dosage: 4 μg per injection Administration: Third-ventricle injection, twice injected for 7 days Result: Improved glucose intolerance and lowered fasting blood insulin levels, and both effects were independent of body weight.
References

[1]. Zhang H, et al. Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models. PLoS One. 2013 May 20;8(5):e61477.  

 Chemical & Physical Properties

Density 1.216g/cm3
Boiling Point 1475.3ºC at 760 mmHg
Molecular Formula C45H69N11O12
Molecular Weight 956.09600
Flash Point 846ºC
Exact Mass 955.51300
PSA 373.51000
LogP 2.09780
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.531

 Synonyms

tyr-ile-gln-asn-asu-pro-leu-gly-nh2