292633-16-0

292633-16-0 structure

Name: Ac-Leu-Glu-His-Asp-AMC trifluoroacetate salt
Chemical Name: ac-leu-glu-his-asp-amc
CAS Number: 292633-16-0
Molecular Formula: C₃₃H₄₁N₇O₁₁
Molecular Weight: 711.719
Catalog: Signaling Pathways Apoptosis Caspase
Create Date: 2018-12-15 17:04:36
Modify Date: 2024-01-09 17:04:18
Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1].

Name	ac-leu-glu-his-asp-amc
Synonyms	N-Acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine ac-lehd-amc trifluoroacetate salt L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- ac-lehd-amc ac-lehd-mca n-acetyl-leu-glu-his-asp-7-amino-4-methylcoumarin amc ac-leu-glu-his-asp-mca ac-leu-glu-his-asp-7-amino-4-methylcoumarin

Description	Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Apoptosis >> Caspase
References	[1]. Igor M Prudnikov, et al. Short peptide tools for monitoring caspase and proteasome activities in embryonal and adult rat brain lysates: an approach for the differential identification of proteases. J Biochem. 2012 Mar;151(3):299-316.