724709-68-6

724709-68-6 structure

Name: Psora-4
Chemical Name: 4-(4-phenylbutoxy)furo[3,2-g]chromen-7-one
CAS Number: 724709-68-6
Molecular Formula: C₂₁H₁₈O₄
Molecular Weight: 334.36500
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2016-11-27 17:27:05
Modify Date: 2024-01-12 14:45:16
Psora-4 is a potent and selective inhibitor of Kv1.3 (voltage-gated potassium channels) with an EC50 of 3 nM[1]. Psora-4 has immunosuppressive activity and inhibits proliferation of human and rat myelin-specific effector memory T cells in vitro[2].

Name	4-(4-phenylbutoxy)furo[3,2-g]chromen-7-one
Synonyms	Lopac-P-9872 5-(4-Phenylbutoxy)psoralen Psora-4

Description	Psora-4 is a potent and selective inhibitor of Kv1.3 (voltage-gated potassium channels) with an EC50 of 3 nM[1]. Psora-4 has immunosuppressive activity and inhibits proliferation of human and rat myelin-specific effector memory T cells in vitro[2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Vennekamp J, et al. Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators. Mol Pharmacol. 2004 Jun;65(6):1364-74.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335-H413
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	C
RIDADR	NONH for all modes of transport