66536-81-0

66536-81-0 structure

Name: Uridine-5-oxyacetic acid methyl ester
Chemical Name: methyl uridin-5-yloxyacetate
CAS Number: 66536-81-0
Molecular Formula: C₁₂H₁₆N₂O₉
Molecular Weight: 332.26
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-07-23 05:45:27
Modify Date: 2024-01-22 12:38:27
Uridine 5-oxyacetic acid methyl ester is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	methyl uridin-5-yloxyacetate
Synonyms	Methyluridine-5-oxyacetic acid methyl 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]oxyacetate 5-(2-methoxy-2-oxoethoxy)uridine uridine-5-oxyacetic acid-methylester 5-methoxycarbonylmethoxyuridine

Description	Uridine 5-oxyacetic acid methyl ester is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.