477-49-6
477-49-6 structure
- Name: Podophyllotoxinone
- Chemical Name: (-)-podophyllotoxon
- CAS Number: 477-49-6
- Molecular Formula: C22H20O8
- Molecular Weight: 412.38900
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
- Create Date: 2018-09-01 08:04:59
- Modify Date: 2024-01-12 10:15:18
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Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization[1].
| Name | (-)-podophyllotoxon |
|---|---|
| Synonyms | Podophyllotoxone |
| Description | Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization[1]. |
|---|---|
| Related Catalog | |
| Target |
Microtubule/Tubulin[1] |
| In Vitro | Podophyllotoxone inhibits human prostate cancer cells PC3 and DU145 growth with IC50 values of 14.7 and 20.6 µM[1]. |
| References |
| Density | 1.365 g/cm3 |
|---|---|
| Boiling Point | 602.3±55.0℃ at 760 mmHg |
| Melting Point | 191.73℃ |
| Molecular Formula | C22H20O8 |
| Molecular Weight | 412.38900 |
| Exact Mass | 412.11600 |
| PSA | 89.52000 |
| LogP | 2.55850 |
| Vapour Pressure | 1.83E-14mmHg at 25°C |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
