26266-58-0

26266-58-0 structure

Name: Sorbitan, tri-(9Z)-9-octadecenoate
Chemical Name: sorbitan trioleate
CAS Number: 26266-58-0
Molecular Formula: C₆₀H₁₀₈O₈
Molecular Weight: 957.495
Catalog: Surfactant Nonionic surfactant Polyol ester type
Create Date: 2018-07-04 14:33:43
Modify Date: 2024-01-11 17:41:19
Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD≥200 mg/kg). Sorbitan trioleate can be used as an excipient, such as surfactant, emulsifier, lubricant, wetting agent, dispersant, thickener, defoamer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

Name	sorbitan trioleate
Synonyms	1,4-anhydro-2,3,6-tri-O--(9Z)-octadec-9-enoyl-D-glucitol emsorb2503 te33 SPAN NO 85 EINECS 247-569-3 Sorbitane trioleate Sorbitan, tri-(9Z)-9-octadecenoate 1,4-anhydro-2,3,6-tri-O--(9Z)-octadec-9-enoyl-L-iditol ionets85 SPAN 85 (Sorbitan Trioleate) L-iditol, 1,4-anhydro-2,3,6-tris-O-[(9Z)-1-oxo-9-octadecenyl]- SPAN(R) 85 L-Iditol, 1,4-anhydro-2,3,6-tris-O-[(9Z)-1-oxo-9-octadecen-1-yl]- MFCD00133820 op85r glycomulto crill5 1,4-Anhydro-2,3,6-tri-O--(9Z)-9-octadecenoyl-L-iditol emasol430

Description	Sorbitan trioleate is an orally active nonionic surfactant with low toxicity (LD≥200 mg/kg). Sorbitan trioleate can be used as an excipient, such as surfactant, emulsifier, lubricant, wetting agent, dispersant, thickener, defoamer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. YAMAMOTO H, et al. Study on subacute toxicity of intravenous sorbitan trioleate (STO) in Wistar rats[J]. The Journal of Toxicological Sciences, 1983, 8(4): 301-310. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),65,1985

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(3),65,1985 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Blood - changes in spleen Blood - changes in erythrocyte (RBC) count

REFERENCE :: JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 8,301,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82920 No. of Facilities: 416 (estimated) No. of Industries: 16 No. of Occupations: 25 No. of Employees: 19949 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82920 No. of Facilities: 1632 (estimated) No. of Industries: 17 No. of Occupations: 21 No. of Employees: 25056 (estimated) No. of Female Employees: 5808 (estimated)

Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi
Risk Phrases	R38
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	WG2934550
HS Code	2932190090

HS Code	2932190090
Summary	2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%