140158-50-5
140158-50-5 structure
- Name: ATPA
- Chemical Name: ATPA,(RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoicacid
- CAS Number: 140158-50-5
- Molecular Formula: C10H16N2O4
- Molecular Weight: 228.24500
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
- Create Date: 2017-05-17 15:55:41
- Modify Date: 2024-01-04 23:38:54
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ATPA is a selective glutamate receptor GluR5 activator with EC50s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S741M), GluR5(S721T), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V), respectively[1].
| Name | ATPA,(RS)-2-Amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoicacid |
|---|---|
| Synonyms |
16,16-Dimethyl Prostaglandin E2
ATPA |
| Description | ATPA is a selective glutamate receptor GluR5 activator with EC50s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S741M), GluR5(S721T), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V), respectively[1]. |
|---|---|
| Related Catalog | |
| In Vitro | ATPA also activates GluR1wt, GluR1(M722S), GluR1(T700S), GluR1(T700S, M722S), GluR1(M722A) with EC50s of 62, 4.6, 97, 14, 97 μM, respectively[1]. |
| References |
| Density | 1.264g/cm3 |
|---|---|
| Boiling Point | 406.8ºC at 760mmHg |
| Molecular Formula | C10H16N2O4 |
| Molecular Weight | 228.24500 |
| Flash Point | 199.9ºC |
| Exact Mass | 228.11100 |
| PSA | 109.58000 |
| LogP | 1.33240 |
| Vapour Pressure | 2.38E-07mmHg at 25°C |
| Index of Refraction | 1.529 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |