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127299-93-8

127299-93-8 structure
127299-93-8 structure
  • Name: BRL 37344, sodium salt
  • Chemical Name: BRL 37344 sodium salt hydrate
  • CAS Number: 127299-93-8
  • Molecular Formula: C19H21ClNNaO4
  • Molecular Weight: 385.81700
  • Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
  • Create Date: 2018-09-04 08:40:11
  • Modify Date: 2024-01-02 10:06:51
  • BRL 37344 sodium (BRL 37344A) is a specific β3-adrenergic receptor agonist. BRL 37344 sodium treatment significantly lowers the body weight of obese mice[1].

Name BRL 37344 sodium salt hydrate
Synonyms sodium,2-[4-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]acetate
Description BRL 37344 sodium (BRL 37344A) is a specific β3-adrenergic receptor agonist. BRL 37344 sodium treatment significantly lowers the body weight of obese mice[1].
Related Catalog
Target

β3-adrenergic receptor[1]

In Vivo BRL37344 sodium (BRL 37344A) treatment significantly lowers the body weight of obese mice[1]. Animal Model: Five-week-old male Imprinting Control Region (ICR) mice[1] Dosage: 2.5 mg/kg Administration: Intraperitoneal injection; three times per week for two weeks Result: Lowered the body weight of obese mice.
References

[1]. Wu C, et al. Activating brown adipose tissue for weight loss and lowering of blood glucose levels: a microPET study using obese and diabetic model mice. PLoS One. 2014 Dec 2;9(12):e113742.

Boiling Point 569.7ºC at 760mmHg
Molecular Formula C19H21ClNNaO4
Molecular Weight 385.81700
Flash Point 298.4ºC
Exact Mass 385.10600
PSA 81.62000
LogP 2.11380
Vapour Pressure 8.09E-14mmHg at 25°C
Safety Phrases S22-S24/25