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  • DC Chemicals Limited
  • China
  • Product Name: Azlin
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  • Purity: 98.0%
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  • Contact: Tony Cao

37091-66-0

37091-66-0 structure
37091-66-0 structure
  • Name: Azlocillin
  • Chemical Name: azlocillin
  • CAS Number: 37091-66-0
  • Molecular Formula: C20H23N5O6S
  • Molecular Weight: 461.491
  • Catalog: API Antibiotics Penicillin
  • Create Date: 2018-02-26 08:00:00
  • Modify Date: 2024-01-11 18:57:27
  • Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection[1][2].

Name azlocillin
Synonyms (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxo-1-imidazolidinyl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Azlocillin
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]-2-phenylacetyl]amino]-, (2S,5R,6R)-
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-((R)-2-(2-oxo-1-imidazolidinecarboxamido)-2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
Description Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection[1][2].
Related Catalog
References

[1]. Sanders CC. Azlocillin: a new broad spectrum penicillin. J Antimicrob Chemother. 1983 May;11 Suppl B:21-31.  

[2]. Pothineni VR, et al. Azlocillin can be the potential drug candidate against drug-tolerant Borrelia burgdorferi sensu stricto JLB31. Sci Rep. 2020 Mar 2;10(1):3798.  

Density 1.6±0.1 g/cm3
Molecular Formula C20H23N5O6S
Molecular Weight 461.491
Exact Mass 461.136902
PSA 173.45000
LogP -0.34
Index of Refraction 1.697

~89%

37091-66-0 structure

37091-66-0

Literature: Koenig, Hans-Bodo; Metzer, Karl-Georg; Offe, Hans-Albert; Schroeck, Wilfried European Journal of Medicinal Chemistry, 1982 , vol. 17, # 1 p. 59 - 63

~%

37091-66-0 structure

37091-66-0

Literature: Koenig, Hans-Bodo; Metzer, Karl-Georg; Offe, Hans-Albert; Schroeck, Wilfried European Journal of Medicinal Chemistry, 1982 , vol. 17, # 1 p. 59 - 63