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642091-68-7

642091-68-7 structure
642091-68-7 structure
  • Name: Boc-N-Amido-PEG3-azide
  • Chemical Name: tert-butyl N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]carbamate
  • CAS Number: 642091-68-7
  • Molecular Formula: C13H26N4O5
  • Molecular Weight: 318.36900
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-08-07 01:57:35
  • Modify Date: 2024-01-14 11:17:56
  • Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name tert-butyl N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]carbamate
Synonyms 5,8,11-Trioxa-2-azatridecanoic acid,13-azido-,1,1-dimethylethyl ester
t-Boc-N-Amido-PEG3-Azide
1-Boc-amine-11-azido-3,6,9-trioxaundecane
Description Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C13H26N4O5
Molecular Weight 318.36900
Exact Mass 318.19000
PSA 119.26000
LogP 1.52836