- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 3,6,9-Trioxaundecanedioic acid
- Price:
- Purity: 70.0%
- Stocking Period: 10 Day
- Contact: Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 3,6,9-Trioxaundecanedioic acid
- Price: ￥808.0/25g ￥2688.0/100g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: PEG3-(CH2CO2H)2
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: 3,6,9-Trioxaundecanedioic acid
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
13887-98-4
13887-98-4 structure
- Name: 3,6,9-Trioxaundecanedioic acid
- Chemical Name: 3,6,9-Trioxaundecanedioic acid
- CAS Number: 13887-98-4
- Molecular Formula: C8H14O7
- Molecular Weight: 222.193
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-08 23:03:52
- Modify Date: 2024-01-06 14:48:03
-
369-Trioxaundecanedioic Acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3,6,9-Trioxaundecanedioic acid |
|---|---|
| Synonyms |
2,2'-[Oxybis(2,1-ethanediyloxy)]diacetic acid
2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]acetic acid 2,2'-[Oxybis(ethane-2,1-diyloxy)]diacetic acid Acetic acid, 2,2'-[oxybis(2,1-ethanediyloxy)]bis- |
| Description | 369-Trioxaundecanedioic Acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 443.7±30.0 °C at 760 mmHg |
| Molecular Formula | C8H14O7 |
| Molecular Weight | 222.193 |
| Flash Point | 178.3±18.1 °C |
| Exact Mass | 222.073959 |
| PSA | 102.29000 |
| LogP | -1.96 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.474 |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Risk Phrases | 41 |
| Safety Phrases | 26-39 |
| RIDADR | UN 1760 |
| Packaging Group | III |
| HS Code | 2918990090 |
|
~98%
13887-98-4 |
| Literature: Bright, Sandra A.; Brinko, Anne; Larsen, Maja Thim; Sinning, Steffen; Williams, D. Clive; Jensen, Henrik H. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1220 - 1224 |
|
~51%
13887-98-4 |
| Literature: Tetrahedron, , vol. 38, # 22 p. 3299 - 3308 |
|
~%
13887-98-4 |
| Literature: Tetrahedron, , vol. 38, # 14 p. 2055 - 2060 |
| Precursor 1 | |
|---|---|
| DownStream 4 | |
![2,2'-[oxybis(ethyleneoxy)]bisacetyl dichloride structure](https://image.chemsrc.com/caspic/112/31255-25-1.png)
![1-(3,5-dimethylpyrazol-1-yl)-2-[2-(3,5-dimethylpyrazol-1-yl)-2-oxoethoxy]ethanone structure](https://image.chemsrc.com/caspic/493/93274-34-1.png)
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |