98627-69-1
98627-69-1 structure
- Name: 1,3-Bis-aminooxy propane
- Chemical Name: O-(3-aminooxypropyl)hydroxylamine
- CAS Number: 98627-69-1
- Molecular Formula: C3H10N2O2
- Molecular Weight: 106.12400
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-07-20 00:43:59
- Modify Date: 2024-01-12 18:45:24
-
1,3-Bis-aminooxy propane is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | O-(3-aminooxypropyl)hydroxylamine |
|---|---|
| Synonyms |
hydroxylamine-O-[3-(aminooxy)propyl]
1,3-diaminoxypropane 1.3-Bis-aminooxy-propan 1,3-bis-aminooxy-propane O,O'-propane-1,3-diyl-bis-hydroxylamine Hydroxylamine,O,O'-1,3-propanediylbis |
| Description | 1,3-Bis-aminooxy propane is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C3H10N2O2 |
|---|---|
| Molecular Weight | 106.12400 |
| Exact Mass | 106.07400 |
| PSA | 70.50000 |
| LogP | 0.55770 |
|
~%
98627-69-1 |
| Literature: Bauer,L.; Suresh,K.S. Journal of Organic Chemistry, 1963 , vol. 28, p. 1604 - 1608 |
|
~%
Detail
|
| Literature: Novo Nordisk A/S Patent: US2011/306551 A1, 2011 ; |
