89199-99-5

89199-99-5 structure

Name: Mulberrofuran H
Chemical Name: Mulberrofuran H
CAS Number: 89199-99-5
Molecular Formula: C₂₇H₂₂O₆
Molecular Weight: 442.460
Catalog: Natural product Phenols
Create Date: 2016-11-06 11:34:07
Modify Date: 2024-01-06 20:43:27
Mulberrofuran H is a 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.). Mulberrofuran H demonstrates potent inhibition against substrates L-tyrosine (IC50=4.45 µM) and L-DOPA (IC50=19.70 µM). Mulberrofuran H also shows potent anti-inflammatory and antioxidative activities[1][2][3].

Name	Mulberrofuran H
Synonyms	Mulberrofuran H 5-(6-Hydroxy-1-benzofuran-2-yl)-2-[(1S,9S)-5-hydroxy-9-methyl-8-oxatricyclo[7.3.1.0]trideca-2,4,6,10-tetraen-11-yl]-1,3-benzenediol 1,3-Benzenediol, 2-[(2S,6S)-5,6-dihydro-9-hydroxy-2-methyl-2,6-methano-2H-1-benzoxocin-4-yl]-5-(6-hydroxy-2-benzofuranyl)-

Description	Mulberrofuran H is a 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.). Mulberrofuran H demonstrates potent inhibition against substrates L-tyrosine (IC50=4.45 µM) and L-DOPA (IC50=19.70 µM). Mulberrofuran H also shows potent anti-inflammatory and antioxidative activities[1][2][3].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor
Target	4.45 µM (L-tyrosine); 19.70 µM (L-DOPA)[3]
References	[1]. Fukai T, et al. Structure of mulberrofuran H, a novel 2-arylbenzofuran derivative from the cultivated mulberry tree (Morus lhou (ser.) Koidz.)[J]. Chemical and pharmaceutical bulletin, 1984, 32(2): 808-811. [2]. Kang J, et al. Five new diels-alder type adducts from the stem and root bark of Morus mongolica. Planta Med. 2006 Jan;72(1):52-9. [3]. Paudel P, et al. Antioxidant and anti-browning property of 2-arylbenzofuran derivatives from Morus alba Linn root bark. Food Chem. 2020 Mar 30;309:125739.

Hazard Codes	Xi