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72093-21-1

72093-21-1 structure
72093-21-1 structure
  • Name: Mastoparan trifluoroacetate salt
  • Chemical Name: mastoparan
  • CAS Number: 72093-21-1
  • Molecular Formula: C70H131N19O15
  • Molecular Weight: 1478.91000
  • Catalog: Biochemical Peptide
  • Create Date: 2018-07-03 11:33:20
  • Modify Date: 2024-01-02 17:35:24
  • Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

Name mastoparan
Synonyms ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2
INLKALAALAKKIL
INLKALAALAKKIL-NH2
Mastoparan
MASTOPARAN VESPULA LEWISII
PE PTIDE FROM WASP VEN
MFCD00076865
H-ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2
MASTOPARAN 4ACOH 6H2O
Description Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.
Related Catalog
In Vitro Mastoparan has an amphiphilic nature and is reported to exert a variety of pharmacological and biochemical effects. Mastoparan induces exocytosis of hormones from anterior pituitary cells. Mastoparan stimulation of prolactin secretion is dose-dependent, time-dependent, reversible and required the presence of calcium. Mastoparan causes translocation of protein kinase C activity from a soluble to a membrane-attached form. Mastoparan is able to increase the intracellular Ca2+ concentration in Fura-2-loaded individual lactotrophs. Mastoparan is also able to interact with GTP-bindmg proteins. Thus, Mastoparan has been shown to facilitate exchange of nucleotides and to stimulate GTPase activity on G-proteins. It has therefore been proposed that the cellular effects of Mastoparan are due to an ability to mimic G-protein-linked agonist-liganded receptors[1].
References

[1]. Mau SE, et al. Mastoparan, a wasp venom peptide, stimulates release of prolactin from cultured rat anterior pituitary cells. J Endocrinol. 1994 Jul;142(1):9-18.

Density 1.15g/cm3
Boiling Point 1676.8ºC at 760 mmHg
Molecular Formula C70H131N19O15
Molecular Weight 1478.91000
Flash Point 967.9ºC
Exact Mass 1478.01000
PSA 568.56000
LogP 7.00350
Appearance white
Index of Refraction 1.525
Storage condition −20°C
Water Solubility H2O: 1 mg/mL, clear, colorless
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

~75%

72093-21-1 structure

72093-21-1

Literature: Saito, Kazuki; Higashijima, Tsutomu; Miyazawa, Tatsuo; Wakimasu, Mitsuhiro; Fujino, Masahiko Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 6 p. 2187 - 2193