Mastoparan trifluoroacetate salt

Modify Date: 2024-01-02 17:35:24

Mastoparan trifluoroacetate salt Structure
Mastoparan trifluoroacetate salt structure
Common Name Mastoparan trifluoroacetate salt
CAS Number 72093-21-1 Molecular Weight 1478.91000
Density 1.15g/cm3 Boiling Point 1676.8ºC at 760 mmHg
Molecular Formula C70H131N19O15 Melting Point N/A
MSDS USA Flash Point 967.9ºC

 Use of Mastoparan trifluoroacetate salt


Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.

 Names

Name mastoparan
Synonym More Synonyms

 Mastoparan trifluoroacetate salt Biological Activity

Description Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.
Related Catalog
In Vitro Mastoparan has an amphiphilic nature and is reported to exert a variety of pharmacological and biochemical effects. Mastoparan induces exocytosis of hormones from anterior pituitary cells. Mastoparan stimulation of prolactin secretion is dose-dependent, time-dependent, reversible and required the presence of calcium. Mastoparan causes translocation of protein kinase C activity from a soluble to a membrane-attached form. Mastoparan is able to increase the intracellular Ca2+ concentration in Fura-2-loaded individual lactotrophs. Mastoparan is also able to interact with GTP-bindmg proteins. Thus, Mastoparan has been shown to facilitate exchange of nucleotides and to stimulate GTPase activity on G-proteins. It has therefore been proposed that the cellular effects of Mastoparan are due to an ability to mimic G-protein-linked agonist-liganded receptors[1].
References

[1]. Mau SE, et al. Mastoparan, a wasp venom peptide, stimulates release of prolactin from cultured rat anterior pituitary cells. J Endocrinol. 1994 Jul;142(1):9-18.

 Chemical & Physical Properties

Density 1.15g/cm3
Boiling Point 1676.8ºC at 760 mmHg
Molecular Formula C70H131N19O15
Molecular Weight 1478.91000
Flash Point 967.9ºC
Exact Mass 1478.01000
PSA 568.56000
LogP 7.00350
Appearance of Characters white
Index of Refraction 1.525
Storage condition −20°C
Water Solubility H2O: 1 mg/mL, clear, colorless

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~75%

Mastoparan trifluoroacetate salt Structure

Mastoparan trif...

CAS#:72093-21-1

Literature: Saito, Kazuki; Higashijima, Tsutomu; Miyazawa, Tatsuo; Wakimasu, Mitsuhiro; Fujino, Masahiko Chemical & Pharmaceutical Bulletin, 1984 , vol. 32, # 6 p. 2187 - 2193

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 Synonyms

ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2
INLKALAALAKKIL
INLKALAALAKKIL-NH2
Mastoparan
MASTOPARAN VESPULA LEWISII
PE PTIDE FROM WASP VEN
MFCD00076865
H-ILE-ASN-LEU-LYS-ALA-LEU-ALA-ALA-LEU-ALA-LYS-LYS-ILE-LEU-NH2
MASTOPARAN 4ACOH 6H2O
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Price: $108/1mg

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