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122520-79-0

122520-79-0 structure
122520-79-0 structure
  • Name: Tyrphostin AG 30
  • Chemical Name: (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid
  • CAS Number: 122520-79-0
  • Molecular Formula: C10H7NO4
  • Molecular Weight: 205.16700
  • Catalog: Biochemical Amino acids and their derivatives Tyrosine derivatives
  • Create Date: 2019-01-13 10:22:45
  • Modify Date: 2024-01-16 17:43:32
  • Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2].
Name (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid
Synonyms 3.4-Dioxy-benzylidencyanessigsaeure
2-cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid
(E)-2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid
AG 30
2-Propenoic acid,2-cyano-3-(3,4-dihydroxyphenyl)-,(E)
Tyrphostin AG 30
(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid
Tyrophostin AG 30
2-Cyan-3-(3,4-dihydroxy-phenyl)-acrylsaeure
Description Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2].
Related Catalog
References

[1]. Volberg T, et al. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 1992 May;11(5):1733-42.

[2]. Wessely O, et al. Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 1997 May;8(5):481-93.
Density 1.559g/cm3
Boiling Point 465.6ºC at 760mmHg
Molecular Formula C10H7NO4
Molecular Weight 205.16700
Flash Point 235.4ºC
Exact Mass 205.03800
PSA 101.55000
LogP 1.08938
Vapour Pressure 1.8E-09mmHg at 25°C
Index of Refraction 1.717
Hazard Codes Xi
Precursor  3

DownStream  0


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title: CAS No. 122520-79-0 | Chemsrc address: https://www.chemsrc.com/en/baike/695679.html

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