1157899-72-3

1157899-72-3 structure

Name: 3-Cyanovinylcarbazole phosphoramidite
Chemical Name: 5'-O-(4,4'-dimethoxytrityl)-3-cyanovinylcarbazole-1'-β-deoxyriboside-3'-O-(cyanoethoxy-N,N-diisopropylamino)phosphoramidite
CAS Number: 1157899-72-3
Molecular Formula: C₅₀H₅₃N₄O₆P
Molecular Weight: 836.95300
Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
Create Date: 2017-08-15 03:28:15
Modify Date: 2024-01-09 13:57:10
3-Cyanovinylcarbazole phosphoramidite is an antiviral drug that inhibits the synthesis of viral DNA. The modified nucleoside in the compound is synthesized by modifying the ribonucleotide with cyano group at the C-3 position, and can be used as a phosphoric acid amide for DNA synthesis[1].

Name	5'-O-(4,4'-dimethoxytrityl)-3-cyanovinylcarbazole-1'-β-deoxyriboside-3'-O-(cyanoethoxy-N,N-diisopropylamino)phosphoramidite
Synonyms	3-cyanovinylcarbazole phosphoramidite

Description	3-Cyanovinylcarbazole phosphoramidite is an antiviral drug that inhibits the synthesis of viral DNA. The modified nucleoside in the compound is synthesized by modifying the ribonucleotide with cyano group at the C-3 position, and can be used as a phosphoric acid amide for DNA synthesis[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
References	[1]. Takashi Sakamoto, et al. DNA photo-cross-linking using 3-cyanovinylcarbazole modified oligonucleotide with threoninol linker. Org Lett. 2015 Feb 20;17(4):936-9.