Name | musk ketone |
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Synonyms |
KETONE MOSCHUS
Acetophenone, 4'-tert-butyl-2',6'-dimethyl-3',5'-dinitro- (8CI) 4-acetyl-1-tert-butyl-3,5-dimethyl-2-nitro-6-aminobenzene 2-acetyl-5-tert-butyl-4,6-dinitroxylene 3-METHYLCYCLOPENTADECANONE (D,L-MUSCONE) EINECS 201-328-9 1-tert-butyl-3,5-dimethyl-2,6-dinitro-4-acetylbenzene 4'-tert-butyl-2',6'-dimethyl-3',5'-dinitroacetophenone 4-tert-butyl-3,5-dinitro-2,6-dimethyl-acetophenone MOSCHUS 3,5-dinitro-2,6-dimethyl-4-t-butylacetophenone 1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone Ketone musk 1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanon Dinitro-tert-butylxylyl methyl ketone MOSCHUS KETON Ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]- Musk ketone MFCD00024271 Acetyl-dinitro-butyl-xylene 1-[2,6-Dimethyl-4-(2-methyl-2-propanyl)-3,5-dinitrophenyl]ethanone |
Description | Musk ketone (MK) is a widely used artificial fragrance. Musk ketone shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis[1][2][3]. |
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Related Catalog | |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 369.0±42.0 °C at 760 mmHg |
Melting Point | 135-139 °C(lit.) |
Molecular Formula | C14H18N2O5 |
Molecular Weight | 294.30 |
Flash Point | 153.2±20.7 °C |
Exact Mass | 294.121582 |
PSA | 108.71000 |
LogP | 3.86 |
Vapour Pressure | 0.0±0.8 mmHg at 25°C |
Index of Refraction | 1.548 |
Stability | Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. |
Water Solubility | Insoluble ( |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
GHS08, GHS09 |
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Signal Word | Warning |
Hazard Statements | H351-H410 |
Precautionary Statements | P273-P281-P501 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
Hazard Codes | F: Flammable;Xn: Harmful; |
Risk Phrases | R11 |
Safety Phrases | S16-S36/37 |
RIDADR | UN1648 3/PG 2 |
WGK Germany | 2 |
RTECS | KM5775841 |
Hazard Class | 3.0 |
~68% 81-14-1 |
Literature: Safaei-Ghomi, Javad; Bamoniri, Abdolhamid Organic Preparations and Procedures International, 2004 , vol. 36, # 2 p. 188 - 191 |
~39% 81-14-1 |
Literature: Synthesis, , # 8 p. 1291 - 1293 |
~55% 81-14-1 |
Literature: Synthesis, , # 8 p. 1291 - 1293 |
~% 81-14-1 |
Literature: Organic Preparations and Procedures International, , vol. 36, # 2 p. 188 - 191 |