62989-33-7
62989-33-7 structure
- Name: Sapropterin
- Chemical Name: (6r,s)-5,6,7,8-tetrahydro-l-biopterin
- CAS Number: 62989-33-7
- Molecular Formula: C9H15N5O3
- Molecular Weight: 241.247
- Catalog: Pharmaceutical intermediate API intermediate
- Create Date: 2018-09-12 17:49:36
- Modify Date: 2024-01-11 19:52:23
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Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin can be used in study of phenylketonuria (PKU)[1].
| Name | (6r,s)-5,6,7,8-tetrahydro-l-biopterin |
|---|---|
| Synonyms |
Sapropterin
(6R,1'R,2'S)-6-(1',2'-dihydroxypropyl)-5,6,7,8-tetrahydrobiopterin 6b-5,6,7,8-Tetrahydro-L-biopterin Dapropterin (6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-4(1H)-pteridinone (6R)-5,6,7,8-tetrahydro-L-biopterin (6R)-Tetrahydrobiopterin 6R-tetahydrobiopterin 6R-Tetrahydro-L-biopterin R-THBP6R-BH4 (6R)-L-erythro-5,6,7,8-Tetrahydrobiopterin sapropterina sapropterinum (6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(1H)-one R-THBP (6R)-5,6,7,8-Tetrahydrobiopterin (6R)-L-erythro-Tetrahydrobiopterin 4(1H)-Pteridinone, 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-, (6R)- [6R-[6R*(1R*,2S*)]]-2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone |
| Description | Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin can be used in study of phenylketonuria (PKU)[1]. |
|---|---|
| Related Catalog |
| Density | 1.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 506.6±60.0 °C at 760 mmHg |
| Molecular Formula | C9H15N5O3 |
| Molecular Weight | 241.247 |
| Flash Point | 260.2±32.9 °C |
| Exact Mass | 241.117493 |
| PSA | 136.29000 |
| LogP | -4.22 |
| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
| Index of Refraction | 1.822 |
| Storage condition | −20°C |
|
~81%
62989-33-7 |
| Literature: Matsuura, Sadao; Murata, Shizuaki; Sugimoto, Takashi Heterocycles, 1985 , vol. 23, # 12 p. 3115 - 3120 |
|
~%
62989-33-7 |
| Literature: Matsuura, Sadao; Murata, Shizuaki; Sugimoto, Takashi Tetrahedron Letters, 1986 , vol. 27, # 5 p. 585 - 588 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |