Name | madecassic acid |
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Synonyms |
Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,5ξ,6β,9ξ,18ξ)-
Brahmanic acid (2α,3β,5ξ,6β,9ξ,18ξ)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic acid 6-Hydroxyasiatic acid 6BETA-HYDROXYASIATIC ACID madecaic acid (2α,3β,6β)-2,3,6,23-Tetrahydroxyurs-12-en-28-oic acid madesica acid MADESIC ACID Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2α,3β,6β)- Madecassicacid Brahmsaeure (1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-8,10,11-Trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-4a(2H)-picenecarboxylic acid Hydroxy asiaticoside Brahmic acid |
Description | Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells[1]. |
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Related Catalog | |
Target |
COX-2 TNF-α IL-1β IL-6 |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 641.7±55.0 °C at 760 mmHg |
Melting Point | 270ºC (dec.) |
Molecular Formula | C30H48O6 |
Molecular Weight | 504.698 |
Flash Point | 355.9±28.0 °C |
Exact Mass | 504.345093 |
PSA | 118.22000 |
LogP | 4.99 |
Vapour Pressure | 0.0±4.3 mmHg at 25°C |
Index of Refraction | 1.591 |
Storage condition | 2-8°C |
~% 18449-41-7 |
Literature: Phytochemistry (Elsevier), , vol. 7, p. 1385 - 1393 |
Precursor 1 | |
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DownStream 0 |