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20535-04-0

20535-04-0 structure
20535-04-0 structure
  • Name: 2-(6-aminopurin-9-yl)-5-methylidene-oxolane-3,4-diol
  • Chemical Name: 2-(6-aminopurin-9-yl)-5-methylideneoxolane-3,4-diol
  • CAS Number: 20535-04-0
  • Molecular Formula: C10H11N5O3
  • Molecular Weight: 249.23
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2016-04-26 05:46:16
  • Modify Date: 2024-01-10 10:28:20
  • 4′,5′-Didehydro-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 2-(6-aminopurin-9-yl)-5-methylideneoxolane-3,4-diol
Synonyms 4',5'-didehydroadenosine
4',5'-didehydro-5'-deoxyadenosine
Description 4′,5′-Didehydro-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.91g/cm3
Boiling Point 591.1ºC at 760 mmHg
Molecular Formula C10H11N5O3
Molecular Weight 249.23
Flash Point 311.3ºC
Exact Mass 249.08600
PSA 119.31000
Vapour Pressure 8.14E-15mmHg at 25°C
Index of Refraction 1.867

~80%

20535-04-0 structure

20535-04-0

Literature: Roche Palo Alto LLC Patent: US2007/42988 A1, 2007 ; Location in patent: Page/Page column 44-45 ;

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20535-04-0 structure

20535-04-0

Literature: Takaku, Hiroshi; Nomoto, Tadaaki; Kimura, Kenji Chemistry Letters, 1981 , p. 1221 - 1224
Precursor  1

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