2-(6-aminopurin-9-yl)-5-methylidene-oxolane-3,4-diol
Modify Date: 2024-01-10 10:28:20
2-(6-aminopurin-9-yl)-5-methylidene-oxolane-3,4-diol structure
|
Common Name | 2-(6-aminopurin-9-yl)-5-methylidene-oxolane-3,4-diol | ||
|---|---|---|---|---|
| CAS Number | 20535-04-0 | Molecular Weight | 249.23 | |
| Density | 1.91g/cm3 | Boiling Point | 591.1ºC at 760 mmHg | |
| Molecular Formula | C10H11N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 311.3ºC | |
Use of 2-(6-aminopurin-9-yl)-5-methylidene-oxolane-3,4-diol4′,5′-Didehydro-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
| Name | 2-(6-aminopurin-9-yl)-5-methylideneoxolane-3,4-diol |
|---|---|
| Synonym | More Synonyms |
| Description | 4′,5′-Didehydro-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.91g/cm3 |
|---|---|
| Boiling Point | 591.1ºC at 760 mmHg |
| Molecular Formula | C10H11N5O3 |
| Molecular Weight | 249.23 |
| Flash Point | 311.3ºC |
| Exact Mass | 249.08600 |
| PSA | 119.31000 |
| Vapour Pressure | 8.14E-15mmHg at 25°C |
| Index of Refraction | 1.867 |
|
~80%
2-(6-aminopurin... CAS#:20535-04-0 |
| Literature: Roche Palo Alto LLC Patent: US2007/42988 A1, 2007 ; Location in patent: Page/Page column 44-45 ; |
|
~%
2-(6-aminopurin... CAS#:20535-04-0 |
| Literature: Takaku, Hiroshi; Nomoto, Tadaaki; Kimura, Kenji Chemistry Letters, 1981 , p. 1221 - 1224 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| 4',5'-didehydroadenosine |
| 4',5'-didehydro-5'-deoxyadenosine |