- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 11-Maleimidoundecanoic acid
- Price: ￥150.0/1g ￥2190.0/25g ￥510.0/5g
- Purity: 97.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 11-Maleimidoundecanoic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
57079-01-3
57079-01-3 structure
- Name: 11-Maleimidoundecanoic acid
- Chemical Name: 11-(2,5-dioxopyrrol-1-yl)undecanoic acid
- CAS Number: 57079-01-3
- Molecular Formula: C15H23NO4
- Molecular Weight: 281.347
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-24 22:19:07
- Modify Date: 2024-01-04 18:11:21
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11-Maleimidoundecanoic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 11-(2,5-dioxopyrrol-1-yl)undecanoic acid |
|---|---|
| Synonyms |
11-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoic acid
11-maleimido-undecanoic acid 1H-Pyrrole-1-undecanoic acid, 2,5-dihydro-2,5-dioxo- UNII-LG78EY7HVB maleimidoundecanoic acid |
| Description | 11-Maleimidoundecanoic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 452.8±18.0 °C at 760 mmHg |
| Melting Point | 89-90ºC |
| Molecular Formula | C15H23NO4 |
| Molecular Weight | 281.347 |
| Flash Point | 227.6±21.2 °C |
| Exact Mass | 281.162720 |
| PSA | 74.68000 |
| LogP | 3.36 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.515 |
| Storage condition | -20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2925190090 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |